Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251638 | 0.91 | MAOB (0.65) | MAOBAKR1B1MAPTHIF1AGABRP | |
| SCHEMBL4256577 | 0.90 | AKR1B1 (0.67) | MAOBAKR1B1MAPTSLC2A1MAPK1 | |
| SCHEMBL4246525 | 0.89 | MAOB (0.56) | MAOBAKR1B1MAPTGABRPGABRD | |
| SCHEMBL4250542 | 0.88 | MAOB (0.51) | MAOBAKR1B1HIF1AGABRPGABRD | |
| SCHEMBL4250366 | 0.88 | MAOB (0.55) | MAOBAKR1B1MAPTGABRPGABRD | |
| SCHEMBL4249323 | 0.87 | MAOB (0.54) | MAOBAKR1B1MAPTMAPK1GABRP | |
| SCHEMBL4258041 | 0.86 | KDM4E (0.53) | MAOBMAPK1GABRPGABRDGABRA1 | |
| SCHEMBL4249935 | 0.84 | AKR1B1 (0.56) | MAOBAKR1B1MAPTGABRPGABRD | |
| SCHEMBL2249264 | 0.84 | POLB (0.52) | MAOBMAPTCA12CA9SMN1; SMN2 | |
| SCHEMBL29592689 | 0.84 | POLB (0.52) | MAOBMAPTCA12CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935252-B1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | UNIV GRONINGEN (NL) | 2017-04-05 | — | — | EP | disclosed |
| EP-2935252-A1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | Rijksuniversiteit te Groningen (NL) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014098597-A1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2014-06-26 | — | — | WO | disclosed |
| CN-101497571-B | Process for producing chromone compound | SUMITOMO CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-1911896-B | Process for producing benzopyrone compound | SUMITOMO CHEMICAL CO | 2010-09-15 | — | — | CN | disclosed |
| EP-2105431-A1 | Process for Producing Chromone Compound | Sumitomo Chemical Company, Limited (JP) | 2009-09-30 | — | — | EP | disclosed |
| EP-2105432-A1 | Process for Producing Chromone Compound | Sumitomo Chemical Company, Limited (JP) | 2009-09-30 | — | — | EP | disclosed |
| CN-101497571-A | Process for producing chromone compound | SUMITOMO CHEMICAL CO (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-100509751-C | Process for producing benzopyranone compound | SUMITOMO CHEMICAL CO (JP) | 2009-07-08 | — | — | CN | disclosed |
| EP-1867626-A2 | Process for producing chromone compound | Sumitomo Chemical Company, Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-7094914-B2 | Process for producing chromone compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-22 | — | — | US | disclosed |
| CN-1649824-A | Process for producing benzopyranone compound | SUMITOMO CHEMICAL CO (JP) | 2005-08-03 | — | — | CN | disclosed |
| US-6903227-B2 | Synthesis of 2-acyl substituted chromanes and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050085664-A1 | Process for producing chromone compound | SUMITOMO CHEMICAL COMPANY, LMITED (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1479667-A1 | PROCESS FOR PRODUCING CHROMONE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-20030233002-A1 | Synthesis of 2-Acyl substituted chromanes and intermediates thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2001092250-A2 | SYNTHESIS OF 2-ACYL SUBSTITUTED CHROMANES AND INTERMEDIATES THEREOF | COR THERAPEUTICS, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085664-A1 | Process for producing chromone compound | ENY2, CDY1; CDY1B, CDYL | MAOB 476/4885AKR1B1 237/4885MAPT 4765/4885 |
| US-20030233002-A1 | Synthesis of 2-Acyl substituted chromanes and intermediates thereof | PLA2G7, PAFAH1B2, PAFAH1B3 | MAOB 412/4885AKR1B1 1364/4885MAPT 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.