SCHEMBL4253786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4251865	0.91	CHRNB2 (0.43)	CHRNB2CHRNA4HTR3AHTR3EHTR3B
	SCHEMBL4250173	0.86	HTR3A (0.56)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL4253808	0.84	SLC6A2 (0.39)	SLC6A2SLC6A4ALDH1A1
	SCHEMBL13806128	0.83	SLC6A2 (0.35)	RETFFAR4SLC6A2SLC6A4
	Hydrochloric Acid SCHEMBL4254246	0.83	SLC6A2 (0.39)	HTR1ASLC6A2SLC6A4HTR7ALDH1A1
	Hydrochloric Acid SCHEMBL5056639	0.83	LMNA (0.35)	RETFFAR4SLC6A2SLC6A4ALDH1A1
	SCHEMBL13806127	0.83	SLC6A2 (0.42)	HTR1ASLC6A2SLC6A4ALDH1A1
	Hydrochloric Acid SCHEMBL4253274	0.82	SLC6A2 (0.42)	HTR1ASLC6A2SLC6A4HTR7ALDH1A1
	SCHEMBL13816295	0.81	HTR3A (0.38)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL4253213	0.80	RET (0.47)	RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.