Methacrylic Acid

Methacrylic Acid

SCHEMBL4254749

C=C(C)C(=O)O.C=C(C)C(=O)OCCO.Cc1cccc2cc3ccccc3cc12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
KDM4E B2RXH2 5/20 0.34
GAA P10253 1/20 0.34
ELANE P08246 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
TARBP2 Q15633 1/20 0.33
THRB P10828 1/20 0.33
MAPT P10636 1/20 0.32
TSHR P16473 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL828938 0.88 TSHR (0.45) POLBAPEX1HTTTDP1ALDH1A1
Methacrylic Acid SCHEMBL560416 0.84 ALDH1A1 (0.50) TDP1ALDH1A1HSD17B10HPGDCYP1A2
Methacrylic Acid SCHEMBL6815378 0.84 ALDH1A1 (0.50) TDP1ALDH1A1HSD17B10HPGDCYP1A2
Methacrylic Acid SCHEMBL4890718 0.77 ALDH1A1 (0.51) POLBAPEX1HTTTDP1ALDH1A1
Toluene SCHEMBL11225215 0.76 POLB (0.46) POLBAPEX1HTTTDP1ALDH1A1
Acetic Acid SCHEMBL27930643 0.76 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDCYP1A2KDM4E
SCHEMBL15302556 0.75 KDM4E (0.45) POLBAPEX1HTTTDP1ALDH1A1
Diphenylether SCHEMBL8065399 0.75 POLB (0.48) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL15302742 0.74 POLB (0.46) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL15302149 0.74 POLB (0.49) POLBAPEX1HTTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7632630-B2 Dyed photoresists and methods and articles of manufacture comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2009-12-15 US disclosed
US-20090220888-A1 Dyed photoresists and methods and articles of manufacture comprising same SHIPLEY COMPANY, L.L.C. (US) 2009-09-03 US disclosed
US-7147983-B1 Dyed photoresists and methods and articles of manufacture comprising same SHIPLEY COMPANY, L.L.C. (US) 2006-12-12 US disclosed
US-20060204892-A1 Dyed photoresists and methods and articles of manufacture comprising same SHIPLEY (US) 2006-09-14 US disclosed
EP-0834770-B1 Dyed photoresists and methods and articles of manufacture comprising same SHIPLEY CO LLC (US) 2003-11-26 EP disclosed
EP-0834770-A2 Dyed photoresists and methods and articles of manufacture comprising same Shipley Company LLC (US) 1998-04-08 EP disclosed