Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13710304 | 0.86 | GAA (0.51) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL1414807 | 0.84 | MAPT (0.52) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28578217 | 0.84 | GAA (0.54) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8196446 | 0.84 | CYP17A1 (0.51) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL14518047 | 0.84 | GAA (0.50) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL29378002 | 0.82 | ALDH1A1 (0.51) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL536638 | 0.82 | ALDH1A1 (0.51) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL22026644 | 0.82 | ALOX5 (0.50) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL24865580 | 0.82 | GAA (0.53) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL15600499 | 0.82 | GAA (0.47) | GAAMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699250-A | Carboxyesterase polypeptides for amide coupling | 科德克希思公司 | 2020-09-22 | — | — | CN | claimed |
| EP-2691452-B1 | CURABLE FLUOROELASTOMER COMPOSITION | DU PONT (US) | 2018-11-28 | — | — | EP | claimed |
| US-8816013-B2 | Curable fluoroelastomer composition | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | claimed |
| EP-2691452-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E.I. Du Pont De Nemours And Company (US) | 2014-02-05 | — | — | EP | claimed |
| US-20130072643-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-21 | — | — | US | claimed |
| WO-2012135782-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-04 | — | — | WO | claimed |
| CN-120081775-A | Preparation method of N-aminoindole | 山东海化集团有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-111699250-B | Carboxylesterase polypeptides for amide coupling | 科德克希思公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115991884-A | Resin microsphere with covalent bonding heavy metal ion probe and application thereof | 华中师范大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-114195676-B | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114195676-A | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114174288-A | Methods of treatment with aminolevulinic acid synthase 2(ALAS2) modulators | 安吉奥斯医药品有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | Ichnos Sciences SA (CH) | 2020-11-03 | — | — | US | disclosed |
| EP-1000018-A2 | UROKINASE INHIBITORS | Abbott Laboratories (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5962496-A | CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO WELLCOME SPA (IT) | 1999-10-05 | — | — | US | disclosed |
| WO-1999005096-A2 | UROKINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1999-02-04 | — | — | WO | disclosed |
| US-5760059-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS, TREATMENT OF NEURODEGENERATIVE DISEASES | GLAXO WELLCOME SPA (IT) | 1998-06-02 | — | — | US | disclosed |
| CN-1133042-A | Indole derivatives as NMDA antagonists | GLAXO SPA (IT) | 1996-10-09 | — | — | CN | disclosed |
| EP-0723541-A1 | INDOLE DERIVATIVES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.p.A. (IT) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010517-A1 | INDOLE DERIVATIVES AS NMDA ANTAGONISTS | GLAXO WELLCOME S.P.A. (IT) | 1995-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | PTGES, PTGS1, PTGIS | GAA 1319/4885MEN1 4011/4885NPC1 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.