Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 11/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250359 | 0.90 | ALOX15 (0.63) | ALOX15LMNANPSR1GRM4KMT2A | |
| SCHEMBL22234240 | 0.78 | ALOX15 (0.77) | ALOX15LMNAGRM4KMT2APYGL | |
| SCHEMBL29387524 | 0.78 | ALOX15 (0.77) | ALOX15LMNAGRM4KMT2APYGL | |
| SCHEMBL4186735 | 0.78 | ALOX15 (0.65) | ALOX15LMNANPSR1GRM4KMT2A | |
| SCHEMBL4252112 | 0.75 | ALOX15 (0.78) | ALOX15GRM4KMT2APYGL | |
| SCHEMBL3946975 | 0.73 | ALOX15 (0.54) | ALOX15NPSR1 | |
| SCHEMBL22256794 | 0.73 | ALOX15 (0.53) | ALOX15LMNAGRM4KMT2A | |
| SCHEMBL22256776 | 0.73 | ALOX15 (0.53) | ALOX15LMNAGRM4KMT2A | |
| SCHEMBL31453202 | 0.72 | ALOX15 (0.57) | ALOX15LMNAKMT2A | |
| SCHEMBL4254281 | 0.71 | ALOX15 (1.00) | ALOX15NPSR1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143455-A1 | Pyrazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-06-04 | — | — | US | disclosed |
| EP-1937645-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007045868-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143455-A1 | Pyrazoles Useful in the Treatment of Inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885LMNA 1584/4885NPSR1 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.