Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560429 | 0.88 | ALDH1A1 (0.47) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL28488115 | 0.81 | KDM4E (0.42) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL21558450 | 0.81 | ATM (0.44) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL6507153 | 0.80 | KDM4E (0.41) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL15240033 | 0.80 | L3MBTL1 (0.42) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL31347599 | 0.80 | KDM4E (0.41) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL9271076 | 0.79 | CA12 (0.48) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL89040 | 0.78 | ATM (0.52) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL28194744 | 0.76 | TSHR (0.43) | LMNATSHRGAAKDM4EALDH1A1 | |
| SCHEMBL29741070 | 0.76 | GAA (0.46) | LMNAGAAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079697-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | Dow AgroSciences LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008057129-A1 | MULTI-SUBSTITUTED PYRIDYL SULFOXIMINES AND THEIR USE AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |