Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560429 | 0.92 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL15758062 | 0.84 | HCAR2 (0.46) | KDM4EALDH1A1TSHRL3MBTL1LMNA | |
| SCHEMBL4255028 | 0.81 | LMNA (0.44) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL21558450 | 0.81 | ATM (0.44) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL6507153 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL15240033 | 0.80 | L3MBTL1 (0.42) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL31347599 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL28573466 | 0.79 | ATM (0.46) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL3558535 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1GAAGLAATM | |
| SCHEMBL29741272 | 0.76 | TSHR (0.39) | KDM4EALDH1A1GAAGLAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793254-B | Azaquinazoline carboxamide derivatives | 默克专利有限公司 | 2020-10-23 | — | — | CN | disclosed |