Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255261 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL4255254 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL6317063 | 0.89 | HPGD (0.47) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL6317067 | 0.89 | HPGD (0.47) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL6317070 | 0.89 | HPGD (0.47) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL10472081 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL5581863 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1HTTNAPRTHSD17B10 | |
| SCHEMBL6316061 | 0.82 | HTT (0.47) | SMN1; SMN2HTTKMT2AMEN1LMNA | |
| SCHEMBL6247575 | 0.82 | HTT (0.47) | SMN1; SMN2HTTKMT2AMEN1LMNA | |
| SCHEMBL6316066 | 0.82 | HTT (0.47) | SMN1; SMN2HTTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012061-A1 | A Method of Treating Cancer | MERCK SHARP & DOHME CORP. | 2009-01-08 | — | — | US | disclosed |
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012061-A1 | A Method of Treating Cancer | KIF5B, MKI67, KIF2C | SMN1; SMN2 3714/4885L3MBTL1 3122/4885HTT 3061/4885 |
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | SMN1; SMN2 201/4885L3MBTL1 3092/4885HTT 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.