Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.44 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.44 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317063 | 1.00 | HPGD (0.47) | HPGDRECQLSMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL6317070 | 1.00 | HPGD (0.47) | HPGDRECQLSMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL4255254 | 0.89 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTL3MBTL1NAPRT | |
| SCHEMBL4255261 | 0.89 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTL3MBTL1NAPRT | |
| SCHEMBL4255264 | 0.89 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTL3MBTL1NAPRT | |
| SCHEMBL21065463 | 0.87 | SOAT2 (0.59) | SOAT2SOAT1HTTALDH1A1ICMT | |
| SCHEMBL21065474 | 0.87 | SOAT2 (0.59) | SOAT2SOAT1HTTALDH1A1ICMT | |
| SCHEMBL5581863 | 0.83 | SMN1; SMN2 (0.50) | HPGDSMN1; SMN2HTTL3MBTL1NAPRT | |
| SCHEMBL10472081 | 0.76 | ALDH1A1 (0.54) | HPGDRECQLSMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL25730771 | 0.76 | THRA (0.52) | THRATHRBCA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | HPGD 2197/4885RECQL 530/4885SMN1; SMN2 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.