Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 12/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605095 | 0.87 | CYP2A6 (0.57) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL364612 | 0.85 | ALDH1A1 (0.62) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3420262 | 0.84 | CYP2A6 (0.54) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL17212160 | 0.81 | ALDH1A1 (0.53) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL368156 | 0.80 | MKNK1 (0.56) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3419995 | 0.80 | CYP2A6 (0.54) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4252554 | 0.80 | ALDH1A1 (0.44) | NPC1POLBMAPK1RAB9AKDM4E | |
| SCHEMBL221022 | 0.79 | ALDH1A1 (0.67) | NPC1POLBMAPK1RAB9AKDM4E | |
| SCHEMBL23091243 | 0.79 | KMT2A (0.52) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3416944 | 0.79 | ALDH1A1 (0.57) | CYP2A6CYP3A4CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1710233-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239860-A1 | NOVEL BENZOFURAN DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USES OF THESE | ADORA2A, ADORA2B, HTR1F | CYP2A6 865/4885CYP3A4 899/4885CYP2C19 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.