SCHEMBL4255564

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4251584	0.81	ALDH1A1 (0.57)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL4573922	0.81	NPBWR1 (0.60)	ALDH1A1HTTSMN1; SMN2NPBWR1MCHR1
	SCHEMBL27865453	0.79	NPC1 (0.41)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL4256051	0.77	ALDH1A1 (0.44)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL27751746	0.77	ALDH1A1 (0.42)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL4256833	0.76	RECQL (0.42)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL27865454	0.76	NPC1 (0.39)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL29451899	0.75	MEN1 (0.47)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL29451976	0.74	MEN1 (0.46)	ALDH1A1HTTNPC1RAB9ALMNA
	SCHEMBL29451496	0.73	MEN1 (0.46)	ALDH1A1HTTNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.