Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556068 | 0.88 | CYP2C19 (0.42) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL10593364 | 0.86 | THRB (0.39) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL10592431 | 0.85 | MEN1 (0.38) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL6536715 | 0.85 | PARP10 (0.39) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL1325624 | 0.83 | THRB (0.37) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL354834 | 0.73 | CYP1A2 (0.43) | MTNR1AMTNR1BGAACYP2C19CYP1A2 | |
| SCHEMBL7116439 | 0.73 | ALDH1A1 (0.41) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL75998 | 0.72 | ALDH1A1 (0.39) | THRBMTNR1AMTNR1BTGM2GAA | |
| Acrylic Acid SCHEMBL27040911 | 0.72 | THRB (0.43) | THRBMTNR1AMTNR1BTGM2GAA | |
| SCHEMBL21057122 | 0.72 | LDHA (0.59) | TGM2GAACYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1012574-B | PROCESS OF PRODUCTION OF ALPHA-HALOPHENOXYALKYL KETONES | BASF AG (DE) | 1991-05-08 | — | — | CN | claimed |
| EP-0150404-B1 | ALPHA-HALOGEN-PHENOXYALKYLKETONES, PHENOXYALKYLKETONES, PROCESSES FOR THEIR PRODUCTION, AND THEIR USE AS INTERMEDIATES FOR THE PRODUCTION OF FUNGICIDES | BASF Aktiengesellschaft (DE) | 1986-11-26 | — | — | EP | claimed |
| CN-85100807-A | The preparation of alpha-halogen phenoxy group alkyl ketone | — | 1986-07-09 | — | — | CN | claimed |
| CN-111518063-A | Method for preparing benzofuran from furan by one-step method | 中国科学技术大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-108409654-A | Tetrahydroisoquinoline -2- bases aryloxyphenoxy alkyl ketone compound with anti-tumor activity and its pharmaceutical applications | 三峡大学 | 2018-08-17 | — | — | CN | disclosed |
| US-7473786-B1 | Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |
| CN-1012574-B | PROCESS OF PRODUCTION OF ALPHA-HALOPHENOXYALKYL KETONES | BASF AG (DE) | 1991-05-08 | — | — | CN | disclosed |
| CN-85100807-A | The preparation of alpha-halogen phenoxy group alkyl ketone | — | 1986-07-09 | — | — | CN | disclosed |
| CN-85100807-A | The preparation of alpha-halogen phenoxy group alkyl ketone | — | 1986-07-09 | — | — | CN | disclosed |
| EP-0150404-A1 | Alpha-halogen-phenoxyalkylketones, phenoxyalkylketones, processes for their production, and their use as intermediates for the production of fungicides | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |