Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24884698 | 0.90 | KDM4E (0.43) | ALDH1A1KDM4ECYP1A2CYP2C19MAPK1 | |
| SCHEMBL19384236 | 0.84 | KDM4E (0.38) | ALDH1A1KDM4ECYP1A2CYP2C19MAPK1 | |
| SCHEMBL4602701 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EAHRCYP1A2CYP2C19 | |
| SCHEMBL15417945 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4ECYP1A2CYP2C19MAPK1 | |
| SCHEMBL89284 | 0.81 | ALDH1A1 (0.39) | ALDH1A1AHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL8264590 | 0.81 | CHRNB4 (0.48) | KDM4ECYP1A2CYP2C19MAPK1CYP2D6 | |
| SCHEMBL10185702 | 0.81 | KDM4E (0.36) | KDM4ECYP1A2CYP2C19MAPK1CYP2D6 | |
| SCHEMBL12178254 | 0.81 | APP (0.47) | ALDH1A1AHRMAPK1MAOBFFAR1 | |
| SCHEMBL4602697 | 0.81 | ALDH1A1 (0.42) | ALDH1A1AHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL12178253 | 0.80 | MAOB (0.38) | ALDH1A1KDM4EAHRMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022100-A1 | ORGANIC COMPOUNDS | MAIBAUM JUERGEN KLAUS (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20090076062-A1 | Organic Compounds | MAIBAUM JUERGEN KLAUS | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022100-A1 | ORGANIC COMPOUNDS | AGTR1, AGTR2, REN | ALDH1A1 233/4885KDM4E 4349/4885AHR 1021/4885 |
| US-20090076062-A1 | Organic Compounds | AGTR1, AGTR2, REN | ALDH1A1 233/4885KDM4E 4349/4885AHR 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.