SCHEMBL4256199

SCHEMBL4256199

C/C(C(=O)O)=C(/c1ccccc1)S(N)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
TSHR P16473 2/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
PARP1 P09874 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA2 P00918 5/20 0.40
CA1 P00915 4/20 0.40
CA9 Q16790 4/20 0.40
CA12 O43570 3/20 0.40
CA14 Q9ULX7 2/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3223439 1.00 CES2 (0.42) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL27480948 0.87 CYP2C19 (0.43) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL8812668 0.82 CES2 (0.43) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL8812678 0.82 CES2 (0.43) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL11832605 0.81 CA2 (0.46) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL11544195 0.80 PTGS2 (0.46) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL11544189 0.80 PTGS2 (0.46) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL27517009 0.76 RAB9A (0.47) TSHRMAPTTDP1CA2CA1
SCHEMBL367456 0.72 CES1 (0.54) CES2CES1TSHRMAPTL3MBTL1
SCHEMBL367453 0.72 CES1 (0.54) CES2CES1TSHRMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
EP-1577087-B1 Planographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2007-01-17 EP disclosed
US-20060246372-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2006-11-02 US disclosed
EP-1577087-A2 Planographic printing plate precursor Fuji Photo Film Co. Ltd. (JP) 2005-09-21 EP disclosed