SCHEMBL425708

SCHEMBL425708

CC(=O)NNc1ccc(Br)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
TSHR P16473 3/20 0.63
CYP3A4 P08684 2/20 0.63
ALOX5 P09917 1/20 0.63
ALDH1A1 P00352 5/20 0.56
MAPT P10636 4/20 0.56
KDM4E B2RXH2 2/20 0.56
GFER P55789 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
EPHX1 P07099 1/20 0.52
IDO1 P14902 1/20 0.51
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
CYP1A2 P05177 1/20 0.48
MEN1 O00255 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461879 0.82 GAA (0.62) GAASMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL10942888 0.82 CYP3A4 (0.68) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL20984621 0.82 GAA (0.62) GAASMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL8743016 0.80 KMT2A (0.68) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL424604 0.80 CYP3A4 (0.65) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL2384404 0.78 CYP3A4 (0.63) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL1337003 0.78 CYP3A4 (0.63) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL14001690 0.78 CYP3A4 (0.63) GAASMN1; SMN2TSHRCYP3A4ALOX5
SCHEMBL8601895 0.78 GAA (0.58) GAASMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL8861401 0.78 TSHR (0.63) GAASMN1; SMN2TSHRCYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION OKURA INDUSTRIAL CO LTD (JP) 2026-04-23 US disclosed
EP-4714992-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND Cemedine Co., Ltd. (JP) 2026-03-25 EP disclosed
US-12460073-B2 Curable resin composition, fuel cell, and sealing method THREEBOND CO., LTD. (JP) 2025-11-04 US disclosed
US-12325811-B2 Radical-polymerizable adhesive composition for laminating and bonding steel plates, adhesive laminate, motor, and method for manufacturing adhesive laminate THREEBOND CO., LTD. (JP) 2025-06-10 US disclosed
CN-116377044-B Methods and complexes for sequential translocation of two non-covalently bound complementary nucleic acid strands through a nanopore 牛津纳米孔科技公开有限公司 2025-05-06 CN disclosed
WO-2025074830-A1 ANAEROBIC ADHESIVE COMPOSITION FOR ELECTROMAGNETIC STEEL SHEET 大倉工業株式会社 2025-04-10 WO disclosed
WO-2025057988-A1 ANAEROBIC ADHESIVE COMPOSITION 大倉工業株式会社 2025-03-20 WO disclosed
WO-2025052775-A1 PHOTOCURABLE RESIN COMPOSITION 株式会社スリーボンド 2025-03-13 WO disclosed
WO-2007089031-A1 PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-08-09 WO disclosed
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US disclosed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US disclosed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP disclosed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO disclosed
US-4321349-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1982-03-23 US disclosed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US disclosed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION MAT2B, MAT1A, MMAB GAA 3940/4885SMN1; SMN2 1119/4885TSHR 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.