SCHEMBL424604

SCHEMBL424604

CC(=O)NNc1ccc(C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.65
TSHR P16473 2/20 0.65
ALOX5 P09917 1/20 0.65
TDP1 Q9NUW8 3/20 0.61
PTGS2 P35354 2/20 0.58
GAA P10253 6/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
HTT P42858 2/20 0.55
IDO1 P14902 1/20 0.50
LMNA P02545 1/20 0.50
PKM P14618 2/20 0.48
POLB P06746 2/20 0.48
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 6/20 0.46
MAPT P10636 5/20 0.46
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CRHR1 P34998 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11592594 0.84 PTGS2 (0.66) CYP3A4TSHRALOX5TDP1PTGS2
SCHEMBL9462101 0.84 PTGS2 (0.60) CYP3A4TDP1PTGS2GAASMN1; SMN2
SCHEMBL10942888 0.84 CYP3A4 (0.68) CYP3A4TSHRALOX5TDP1PTGS2
SCHEMBL8743016 0.82 KMT2A (0.68) CYP3A4TSHRALOX5TDP1GAA
SCHEMBL3294840 0.80 KIF11 (0.57) TDP1PTGS2GAASMN1; SMN2HTT
SCHEMBL425708 0.80 GAA (0.63) CYP3A4TSHRALOX5TDP1GAA
SCHEMBL8861401 0.80 TSHR (0.63) CYP3A4TSHRALOX5TDP1PTGS2
SCHEMBL2384404 0.80 CYP3A4 (0.63) CYP3A4TSHRALOX5TDP1PTGS2
SCHEMBL1337003 0.80 CYP3A4 (0.63) CYP3A4TSHRALOX5TDP1PTGS2
SCHEMBL14001690 0.80 CYP3A4 (0.63) CYP3A4TSHRALOX5TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-6852193-B2 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2005-02-08 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
US-20030171467-A1 Semi-solid one- or two-part compositions LOCTITE (R&D) LIMITED (IE) 2003-09-11 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001092434-A1 SEMI-SOLID ONE- OR TWO-PART COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 2001-12-06 WO claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US claimed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US claimed
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION OKURA INDUSTRIAL CO LTD (JP) 2026-04-23 US disclosed
EP-4714992-A1 POLYTETRAMETHYLENE GLYCOL-BASED (METH)ACRYLATE COMPOUND Cemedine Co., Ltd. (JP) 2026-03-25 EP disclosed
US-12460073-B2 Curable resin composition, fuel cell, and sealing method THREEBOND CO., LTD. (JP) 2025-11-04 US disclosed
US-12325811-B2 Radical-polymerizable adhesive composition for laminating and bonding steel plates, adhesive laminate, motor, and method for manufacturing adhesive laminate THREEBOND CO., LTD. (JP) 2025-06-10 US disclosed
WO-2025074830-A1 ANAEROBIC ADHESIVE COMPOSITION FOR ELECTROMAGNETIC STEEL SHEET 大倉工業株式会社 2025-04-10 WO disclosed
US-4321349-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1982-03-23 US disclosed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US disclosed
US-4279987-A 2,5-DIHYDROXY-BIPHENYL COMPOUNDS ADDED AS DEVELOPMENT ACCELERATORS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-21 US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US disclosed
US-4150993-A AMINEBORANE COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109883-A1 ANAEROBIC ADHESIVE COMPOSITION MAT2B, MAT1A, MMAB CYP3A4 1814/4885TSHR 4826/4885ALOX5 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.