SCHEMBL8743016

SCHEMBL8743016

CC(=O)NNc1ccc(NC(C)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.68
MEN1 O00255 3/20 0.68
MAPT P10636 3/20 0.68
ALDH1A1 P00352 3/20 0.68
CYP3A4 P08684 2/20 0.68
TSHR P16473 2/20 0.68
CA12 O43570 2/20 0.68
CA1 P00915 2/20 0.68
CA2 P00918 2/20 0.68
CA9 Q16790 2/20 0.68
BRD4 O60885 1/20 0.68
NR1I2 O75469 1/20 0.68
MB P02144 1/20 0.68
CYP1A1 P04798 1/20 0.68
CA3 P07451 1/20 0.68
RARG P13631 1/20 0.68
ALOX5AP P20292 1/20 0.68
CA4 P22748 1/20 0.68
CA7 P43166 1/20 0.68
NR1I3 Q14994 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9341760 0.87 KMT2A (0.63) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL11680624 0.85 GAA (0.61) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL861674 0.85 SMN1; SMN2 (0.84) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL10942888 0.84 CYP3A4 (0.68) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL10906841 0.82 TSHR (0.78) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL9771265 0.82 L3MBTL1 (0.59) KMT2AMEN1MAPTALDH1A1CYP3A4
SCHEMBL424604 0.82 CYP3A4 (0.65) KMT2AMEN1MAPTALDH1A1CYP3A4
Acetaminophen SCHEMBL3480 0.81 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CYP3A4
Acetaminophen SCHEMBL8937727 0.81 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CYP3A4
Acetaminophen SCHEMBL252939 0.81 KMT2A (1.00) KMT2AMEN1MAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459334-B1 Light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1997-02-05 EP disclosed
EP-0473209-B1 Method of making direct-positive computer output images AGFA GEVAERT NV (BE) 1997-01-02 EP disclosed
US-5449592-A Exposure through black and white halftone images from color separation, different spectral distribution of light, yellow and magenta couplers KONICA CORPORATION (JP) 1995-09-12 US disclosed
EP-0468104-B1 Light-sensitive silver halide material for making direct-positive images AGFA GEVAERT NV (BE) 1994-09-28 EP disclosed
EP-0264192-B1 Direct positive silver halide light-sensitive photographic material KONISHIROKU PHOTO IND (JP) 1994-03-30 EP disclosed
US-5166043-A Photographic films for latent images AGFA-GEVAERT, N.V. (BE) 1992-11-24 US disclosed
US-5155014-A Developing exposed light sensitive element in presence of development nucleator, density increasing compound, hydroqinone type solutions and alkanolamine compounds AGFA-GEVAERT, N.V. (BE) 1992-10-13 US disclosed
EP-0190512-B1 POSITIVE IMAGE FORMING METHOD KONICA CORPORATION (JP) 1992-09-30 EP disclosed
EP-0473209-A1 Method of making direct-positive computer output images AGFA-GEVAERT N.V. (BE) 1992-03-04 EP disclosed
EP-0468104-A1 Light-sensitive silver halide material for making direct-positive images AGFA-GEVAERT N.V. (BE) 1992-01-29 EP disclosed
EP-0308872-A2 Direct positive-type silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1989-03-29 EP disclosed
EP-0306293-A2 Method for processing lightsensitive silver halide color photographic material KONICA CORPORATION (JP) 1989-03-08 EP disclosed
EP-0297836-A2 Silver halide light-sensitive color photographic material excellent in the color reproducibility and method for processing the same KONICA CORPORATION (JP) 1989-01-04 EP disclosed
US-4749644-A DIRECT POSITIVES; STABILITY, SMOOTHNESS, IMAGE QUALITY; COLOR FILM KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-06-07 US disclosed
EP-0264192-A2 Direct positive silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1988-04-20 EP disclosed
EP-0204530-A2 Method for forming direct positive color image KONICA CORPORATION (JP) 1986-12-10 EP disclosed
EP-0190512-A2 Positive image forming method KONICA CORPORATION (JP) 1986-08-13 EP disclosed
US-4279987-A 2,5-DIHYDROXY-BIPHENYL COMPOUNDS ADDED AS DEVELOPMENT ACCELERATORS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-07-21 US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4150993-A AMINEBORANE COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-04-24 US disclosed