Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257218 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KMT2AHTTAPOBEC3GPOLB | |
| SCHEMBL27330043 | 0.79 | KMT2A (0.48) | L3MBTL1KMT2AHTTAPOBEC3GPOLB | |
| SCHEMBL4893960 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBLMNAMAPT | |
| SCHEMBL13754804 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBLMNAMAPT | |
| SCHEMBL13957726 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBLMNAMAPT | |
| SCHEMBL2680934 | 0.79 | L3MBTL1 (0.56) | L3MBTL1KMT2APOLBLMNAMAPT | |
| SCHEMBL4257688 | 0.78 | ALDH1A1 (0.56) | L3MBTL1KMT2AHTTLMNAMAPT | |
| SCHEMBL4257693 | 0.78 | ALDH1A1 (0.56) | L3MBTL1KMT2AHTTLMNAMAPT | |
| SCHEMBL3585094 | 0.72 | RAB9A (0.52) | L3MBTL1KMT2APOLBLMNANPC1 | |
| SCHEMBL4893970 | 0.72 | ALDH1A1 (0.54) | L3MBTL1KMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8853352-B2 | Functionalized polymer and method for making | BRIDGESTONE CORPORATION (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |
| US-20080154020-A1 | introducing imine compounds into carbanionic (living) polymers, that can interact with particle filler such as carbon black and silica | BRIDGESTONE CORPORATION (JP) | 2008-06-26 | — | — | US | disclosed |