Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15133255 | 0.76 | KMT2A (0.43) | ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL9397681 | 0.76 | — | — | |
| SCHEMBL10627206 | 0.76 | GLA (0.35) | ALDH1A1MAPK1GLAKMT2ALMNA | |
| SCHEMBL6639439 | 0.72 | GLA (0.38) | ALDH1A1GLAKMT2ALMNAMAPT | |
| SCHEMBL7383326 | 0.72 | ACHE (0.37) | ALDH1A1MAPK1KMT2ALMNAMAPT | |
| SCHEMBL11062359 | 0.72 | ACHE (0.33) | ALDH1A1MAPK1CRBN | |
| SCHEMBL11551928 | 0.72 | ALDH1A1 (0.33) | ALDH1A1GLAKMT2ALMNAMAPT | |
| SCHEMBL11551937 | 0.72 | ALDH1A1 (0.33) | ALDH1A1GLAKMT2ALMNAMAPT | |
| SCHEMBL6419554 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL6759564 | 0.70 | ALDH1A1 (0.31) | ALDH1A1GLAKMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
| EP-2097420-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | Pfizer Products Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008065508-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | ALDH1A1 212/4885MAPK1 1428/4885NLRP3 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.