Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253252 | 0.79 | FYN (0.40) | FYNCHEK1CHEK2ABL1TYR | |
| SCHEMBL4253156 | 0.79 | FYN (0.41) | FYNCHEK1CHEK2ABL1TYR | |
| SCHEMBL13745284 | 0.79 | TGFBR1 (0.40) | FYNCHEK1CHEK2ABL1TYR | |
| SCHEMBL3029604 | 0.75 | MAP3K14 (0.49) | SCN10A | |
| SCHEMBL13873982 | 0.72 | FYN (0.55) | FYNCHEK1CHEK2ABL1 | |
| SCHEMBL30217954 | 0.72 | MAP3K14 (0.40) | CHEK1SCN10A | |
| SCHEMBL3020269 | 0.72 | POLB (0.51) | — | |
| SCHEMBL3026036 | 0.72 | MAP3K14 (0.33) | SCN10A | |
| Bromide SCHEMBL3016136 | 0.70 | POLB (0.50) | — | |
| SCHEMBL31251397 | 0.70 | ADORA3 (0.47) | FYNCHEK1CHEK2ABL1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232566-B | Amide compound, preparation method thereof and application thereof in herbicide | 中新科农(山东)生态农业有限公司 | 2021-03-12 | — | — | CN | disclosed |
| US-20090215818-A1 | THIOZOLIDINEDIONE DERIVATIVES AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090215818-A1 | THIOZOLIDINEDIONE DERIVATIVES AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215818-A1 | THIOZOLIDINEDIONE DERIVATIVES AS PI3 KINASE INHIBITORS | PIK3CD, PI4KA, PIP4K2A | FYN 115/4885CHEK1 553/4885CHEK2 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.