Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142311 | 0.95 | FFAR1 (0.60) | NR4A2KMT2AHRH3CYP1A2FFAR1 | |
| SCHEMBL2743484 | 0.90 | PDE4B (0.64) | HRH3FFAR1RAB9APDE4BMMP2 | |
| SCHEMBL31322194 | 0.83 | HRH3 (0.49) | HRH3RAB9AMMP2MMP9MMP8 | |
| SCHEMBL18038016 | 0.83 | HRH3 (0.55) | HRH3SMN1; SMN2HPGDMMP2MMP9 | |
| SCHEMBL2092409 | 0.83 | HRH3 (0.49) | HRH3RAB9AMMP2MMP9MMP8 | |
| SCHEMBL31322196 | 0.83 | HRH3 (0.49) | HRH3RAB9AMMP2MMP9MMP8 | |
| SCHEMBL7202267 | 0.82 | CYP1A2 (0.55) | NR4A2KMT2AHRH3CYP1A2FFAR1 | |
| SCHEMBL7190697 | 0.81 | FFAR4 (0.48) | KMT2AHRH3CYP1A2FFAR1LMNA | |
| SCHEMBL16563404 | 0.80 | MAPT (0.53) | HRH3RAB9APDE4BMMP2MMP9 | |
| SCHEMBL28739818 | 0.80 | HTR7 (0.60) | HRH3MMP2MMP9MMP8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | disclosed |
| EP-1379500-A2 | METHOD FOR THE PRODUCTION OF $g(D)?1 PYRROLINES | Bayer CropScience AG (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002081442-A2 | METHOD FOR THE PRODUCTION OF Δ1 PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | NR4A2 103/4885KMT2A 410/4885HRH3 598/4885 |
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | AR, NR5A1, SRD5A1 | NR4A2 1119/4885KMT2A 3262/4885HRH3 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.