Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4142311 | 0.87 | FFAR1 (0.60) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A | |
| SCHEMBL4258765 | 0.82 | NR4A2 (0.53) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A | |
| SCHEMBL10884944 | 0.78 | SMN1; SMN2 (0.88) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A | |
| SCHEMBL2377766 | 0.77 | ALDH1A1 (0.51) | RAB9AHIF1AALDH1A1HSD17B10TSHR | |
| SCHEMBL28012437 | 0.77 | TRPV1 (0.54) | SMN1; SMN2RAB9AALDH1A1HSD17B10TSHR | |
| SCHEMBL850939 | 0.76 | ALDH1A1 (0.77) | ALDH1A1HSD17B10TSHRKMT2ATRPV1 | |
| SCHEMBL7857488 | 0.75 | SMN1; SMN2 (0.66) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A | |
| SCHEMBL7864057 | 0.75 | PDE4B (0.73) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A | |
| SCHEMBL4035963 | 0.73 | ALDH1A1 (0.42) | RAB9AALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL7864069 | 0.73 | SMN1; SMN2 (0.72) | CYP1A2SMN1; SMN2FFAR1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220517-A1 | Method for producing ketocarboxylic acid derivatives | CYP2F1, HK1, FBP1 | CYP1A2 377/4885SMN1; SMN2 4111/4885FFAR1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.