Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563209 | 0.87 | KMT2A (0.42) | POLBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4087454 | 0.87 | ALDH1A1 (0.36) | POLBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL4252376 | 0.87 | ALDH1A1 (0.53) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL1554744 | 0.85 | HSD17B10 (0.47) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1554791 | 0.84 | ALDH1A1 (0.46) | POLBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL1554631 | 0.82 | LMNA (0.42) | ALDH1A1MEN1KMT2AGAARXFP1 | |
| SCHEMBL1553982 | 0.80 | ALDH1A1 (0.52) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1554635 | 0.79 | MEN1 (0.48) | POLBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL1553944 | 0.78 | POLB (0.44) | POLBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1553830 | 0.78 | TNF (0.44) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383463-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | KING PHARMACEUTICALS INC (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-1383463-A2 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | King Pharmaceuticals, Inc. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002083083-A2 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | KING PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |