Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504515 | 0.79 | NOS1 (0.41) | NOS1BLMKDM4EF2PRSS1 | |
| SCHEMBL2959935 | 0.74 | — | — | |
| SCHEMBL27676666 | 0.72 | — | — | |
| SCHEMBL2136922 | 0.72 | — | — | |
| Pimagedine SCHEMBL31430898 | 0.66 | BLM (0.73) | NOS1BLMKDM4EF2PRSS1 | |
| SCHEMBL18373371 | 0.65 | — | — | |
| SCHEMBL1065361 | 0.65 | — | — | |
| SCHEMBL4142691 | 0.64 | — | — | |
| SCHEMBL5345895 | 0.63 | CYP1A2 (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL27857618 | 0.63 | NOS1 (0.36) | NOS1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641121-B | Sheath for cannula | 泰尔茂株式会社 | 2021-09-21 | — | — | CN | disclosed |
| US-20090048667-A1 | Controlled Drug-Release Composition and Drug-Releasable Medical Device | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2009-02-19 | — | — | US | disclosed |
| CN-1057670-C | Prolonged release preparation and polymers thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-10-25 | — | — | CN | disclosed |
| CN-1043189-C | Method for preparing sustained-release medicament | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-05-05 | — | — | CN | disclosed |
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5140048-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0327919-A2 | Method and agents for preventing staining of teeth | THE ROCKEFELLER UNIVERSITY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048667-A1 | Controlled Drug-Release Composition and Drug-Releasable Medical Device | LDLR, SRR, PLAUR | NOS1 1273/4885BLM 1668/4885KDM4E 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.