SCHEMBL9504515

SCHEMBL9504515

NN=C(N)NOS(=O)(=O)ONC(N)=NN

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.41
BLM P54132 1/20 0.36
KDM4E B2RXH2 1/20 0.36
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
AOC1 P19801 1/20 0.30
NFKB1 P19838 1/20 0.30
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4259788 0.79 NOS1 (0.38) NOS1BLMKDM4EF2PRSS1
SCHEMBL2511148 0.71 TSHR (0.37) BLMMEN1CYP1A2CYP3A4TSHR
Water SCHEMBL28060703 0.69 TSHR (0.35) BLMMEN1CYP1A2CYP3A4TSHR
SCHEMBL7525108 0.69 ALDH1A1 (0.35)
SCHEMBL27509677 0.69
SCHEMBL1551834 0.67 CA2 (0.44) F2PRSS1PRSS2PRSS3
SCHEMBL507711 0.67 NOS1 (0.41) NOS1BLMKDM4EF2PRSS1
SCHEMBL40803 0.67 NOS1 (0.41) NOS1BLMKDM4EMEN1CYP1A2
Hydrochloric Acid SCHEMBL3279131 0.65 NOS1 (0.39) NOS1BLM
SCHEMBL1551842 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331821-B1 ANTIVIRAL AGENT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
EP-0331821-A1 Antiviral agent KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed