Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13931458 | 0.80 | CYP19A1 (0.42) | ALDH1A1CYP19A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL3493878 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP19A1TSHRRECQLPOLB | |
| SCHEMBL5393595 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CYP19A1TSHRRECQLLMNA | |
| SCHEMBL4265207 | 0.74 | NOTUM (0.48) | ALDH1A1TSHRPOLBLMNAGAA | |
| SCHEMBL3491679 | 0.73 | ALDH1A1 (0.65) | ALDH1A1CYP19A1TSHRPOLBLMNA | |
| SCHEMBL5381957 | 0.73 | RECQL (0.46) | ALDH1A1CYP19A1TSHRRECQLLMNA | |
| SCHEMBL7593612 | 0.72 | CYP19A1 (0.46) | ALDH1A1CYP19A1TSHRRECQLPOLB | |
| SCHEMBL6596242 | 0.72 | GAA (0.57) | ALDH1A1CYP19A1TSHRRECQLGAA | |
| SCHEMBL6596244 | 0.72 | GAA (0.57) | ALDH1A1CYP19A1TSHRRECQLGAA | |
| SCHEMBL5393696 | 0.72 | RECQL (0.49) | ALDH1A1CYP19A1TSHRRECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | ALDH1A1 435/4885CYP19A1 956/4885TSHR 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.