Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998144 | 0.82 | HTR6 (0.45) | PIK3CDSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL19667310 | 0.73 | USP2 (0.44) | USP2SMN1; SMN2ESR2GPR119NR1H2 | |
| SCHEMBL4260447 | 0.73 | HTR2A (0.38) | PIK3CDUSP2SMN1; SMN2ESR2GPR119 | |
| SCHEMBL3276399 | 0.72 | UCHL1 (0.44) | USP2SMN1; SMN2ESR2GPR119NR1H2 | |
| SCHEMBL17813928 | 0.72 | USP2 (0.43) | USP2SMN1; SMN2ESR2GPR119NR1H2 | |
| SCHEMBL17813927 | 0.72 | NR1H2 (0.44) | PIK3CDUSP2SMN1; SMN2ESR2GPR119 | |
| SCHEMBL20283307 | 0.71 | USP2 (0.43) | USP2SMN1; SMN2ESR2RIPK1MEN1 | |
| SCHEMBL19667083 | 0.71 | ESR2 (0.44) | PIK3CDUSP2SMN1; SMN2ESR2RIPK1 | |
| SCHEMBL1997743 | 0.71 | CREBBP (0.43) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL3276273 | 0.70 | UCHL1 (0.49) | USP2SMN1; SMN2GPR119MAPK1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091953-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4]OXAZEPINO [6, 7-E]INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (publ) (SE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |