Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712688 | 1.00 | KMT2A (0.51) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| SCHEMBL30047330 | 0.86 | PTGS1 (0.48) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| SCHEMBL5661600 | 0.86 | PTGS1 (0.48) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| SCHEMBL5661601 | 0.86 | PTGS1 (0.48) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| SCHEMBL11203097 | 0.84 | KMT2A (0.49) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| SCHEMBL11058766 | 0.84 | KMT2A (0.49) | KMT2ANPC1RAB9AALDH1A1AKR1C3 | |
| Hydrochloric Acid SCHEMBL6133017 | 0.83 | TSHR (0.49) | KMT2ANPC1RAB9AALDH1A1HDAC1 | |
| SCHEMBL11599210 | 0.82 | RAPGEF4 (0.43) | LMNAPTGS1PTGS2 | |
| SCHEMBL11599212 | 0.82 | RAPGEF4 (0.43) | LMNAPTGS1PTGS2 | |
| SCHEMBL29180082 | 0.80 | MAPT (0.57) | NPC1RAB9AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047687-A1 | Indane Acetic Acid Derivatives and Their Use as Pharmaceutical Agents, Intermediates, and Method of Preparation | LOWE DEREK B | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047687-A1 | Indane Acetic Acid Derivatives and Their Use as Pharmaceutical Agents, Intermediates, and Method of Preparation | INSR, ACACA, IAPP | KMT2A 1951/4885NPC1 300/4885RAB9A 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.