Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 9/20 | 0.36 |
| ▸ | MGAM | O43451 | 8/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.36 |
| ▸ | SI | P14410 | 8/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427200 | 0.91 | NAMPT (0.45) | NAMPTF12GAAMGAMAMY1A | |
| SCHEMBL444875 | 0.90 | HCAR3 (0.40) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL425750 | 0.89 | TRPV1 (0.38) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL426102 | 0.87 | FAAH (0.42) | F12GAAMGAMAMY1ASI | |
| SCHEMBL425936 | 0.86 | KCNMA1 (0.39) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL427865 | 0.84 | PDE2A (0.39) | KMT2AHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL427401 | 0.84 | MAPT (0.47) | GAAKMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL427663 | 0.84 | FAAH (0.36) | F12GAAMGAMAMY1ASI | |
| SCHEMBL425578 | 0.83 | FAAH (0.47) | F12GAAMGAMAMY1ASI | |
| SCHEMBL427772 | 0.83 | KCNMA1 (0.41) | NAMPTGAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-9353082-B2 | Pharmaceutical compounds | BIAL—PORTELA & CA, S.A. (PT) | 2016-05-31 | — | — | US | disclosed |
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065191-A1 | PHARMACEUTICAL COMPOUNDS | FAAH, FAAH2, ASAH1 | NAMPT 372/4885F12 785/4885GAA 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.