Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | PIM1 | P11309 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860539 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL351486 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL28384025 | 0.84 | ALDH1A1 (0.95) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| Bicarbonate SCHEMBL11185192 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL47270 | 0.81 | MAPT (0.54) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL43146 | 0.81 | MAPT (0.54) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL6991670 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL9688082 | 0.79 | ACHE (0.59) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL7968125 | 0.79 | ACHE (0.59) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL3696226 | 0.77 | PIM1 (0.56) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| EP-3858356-A2 | SYSTEMS, METHODS, AND COMPOSITIONS FOR CROSS-LINKING | Avedro, Inc. (US) | 2021-08-04 | — | — | EP | claimed |
| US-10620207-B2 | Method of identifying treatment responsive non-small cell lung cancer using anaplastic lymphoma kinase (ALK) as a marker | VENTANA MEDICAL SYSTEMS, INC. (US) | 2020-04-14 | — | — | US | claimed |
| US-10145852-B2 | Multiples multiplex immunohistochemical assay using primary antibodies of the same host species | VENTANA MEDICAL SYSTEMS, INC. (US) | 2018-12-04 | — | — | US | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20180106816-A1 | MULTIPLES MULTIPLEX IMMUNOHISTOCHEMICAL ASSAY USING PRIMARY ANTIBODIES OF THE SAME HOST SPECIES | VENTANA MEDICAL SYSTEMS, INC. | 2018-04-19 | — | — | US | claimed |
| CN-104603620-B | The method of identification treatment response non-small cell lung cancer using anaplastic lymphoma kinase (ALK) as mark | 文塔纳医疗系统公司 | 2018-02-23 | — | — | CN | claimed |
| US-9874571-B2 | Multiplex immunohistochemical assay using primary antibodies of the same host species | VENTANA MEDICAL SYSTEMS, INC. (US) | 2018-01-23 | — | — | US | claimed |
| US-20170234886-A1 | MULTIPLES IMMUNOHISTOCHEMICAL ASSAY USING PRIMARY ANTIBODIES OF THE SAME HOST SPECIES | VENTANA MEDICAL SYSTEMS, INC. | 2017-08-17 | — | — | US | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-10-18 | — | — | US | claimed |
| US-6248161-B1 | Preparation of permanent color inks from water-soluble colorants using specific phosphonium salts | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| US-5854008-A | Europium and terbium chelators for the time-resolved fluorometric assays | NORDION INTERNATIONAL, INC. (CA) | 1998-12-29 | — | — | US | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | claimed |
| US-5430175-A | Caged carboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-07-04 | — | — | US | claimed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885MAPT 2153/4885SMN1; SMN2 4271/4885 |
| US-20070243519-A1 | Protecting group for carboxylic acids that can be photolyzed by visible light | CYBA, ALDH3A1, HCCS | ALDH1A1 37/4885MAPT 2645/4885SMN1; SMN2 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.