Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.62 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976006 | 0.77 | FDPS (1.00) | FDPSGGPS1HDAC6HDAC1LTA4H | |
| SCHEMBL13044929 | 0.76 | HDAC6 (0.47) | FDPSHDAC6HDAC1LTA4H | |
| SCHEMBL3977299 | 0.72 | FDPS (0.63) | FDPSGGPS1HDAC6HDAC1CYP3A4 | |
| SCHEMBL30013008 | 0.72 | HDAC6 (0.47) | FDPSHDAC6HDAC1LTA4HCYP3A4 | |
| SCHEMBL338773 | 0.72 | HDAC6 (0.52) | FDPSHDAC6HDAC1LTA4H | |
| SCHEMBL48336 | 0.71 | ADORA2A (0.47) | FDPSHDAC6HDAC1LTA4H | |
| SCHEMBL20385726 | 0.70 | FDPS (1.00) | FDPSGGPS1HDAC6HDAC1CYP3A4 | |
| SCHEMBL3671304 | 0.68 | LTA4H (0.50) | HDAC6HDAC1LTA4H | |
| SCHEMBL11066170 | 0.68 | ADORA2A (0.50) | HDAC6HDAC1LTA4H | |
| SCHEMBL12472644 | 0.68 | HDAC6 (1.00) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |