Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266919 | 0.86 | MAPT (0.42) | L3MBTL1NPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL4278133 | 0.86 | L3MBTL1 (0.51) | L3MBTL1NPC1ALDH1A1KDM4ETRPM8 | |
| SCHEMBL4265182 | 0.85 | MAPT (0.46) | L3MBTL1ALDH1A1MAPTKDM4EESR1 | |
| SCHEMBL4269415 | 0.81 | TRPM8 (0.50) | L3MBTL1ALDH1A1MAPTKDM4EESR1 | |
| SCHEMBL4264174 | 0.79 | ESR1 (0.50) | L3MBTL1NPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL4551139 | 0.79 | ESR1 (0.50) | L3MBTL1NPC1ALDH1A1MAPTKDM4E | |
| Diethylamine SCHEMBL4562983 | 0.79 | MAPT (0.43) | L3MBTL1NPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL4429251 | 0.76 | EGFR (0.49) | MAPTESR1APP | |
| SCHEMBL4267886 | 0.74 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTKDM4EESR1 | |
| SCHEMBL4273105 | 0.74 | EGFR (0.56) | MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |