Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 9/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263749 | 1.00 | MCHR1 (0.53) | MCHR1CARM1PRMT6CCNT1RIPK2 | |
| SCHEMBL6877502 | 0.85 | MCHR1 (0.59) | MCHR1CARM1PRMT6RIPK2ALDH1A1 | |
| SCHEMBL6877508 | 0.85 | MCHR1 (0.59) | MCHR1CARM1PRMT6RIPK2ALDH1A1 | |
| SCHEMBL4271810 | 0.84 | CARM1 (0.50) | MCHR1CARM1PRMT6CCNT1RIPK2 | |
| SCHEMBL4264985 | 0.83 | LMNA (0.50) | MCHR1CARM1PRMT6CCNT1BCHE | |
| SCHEMBL4264983 | 0.83 | LMNA (0.50) | MCHR1CARM1PRMT6CCNT1BCHE | |
| SCHEMBL4260567 | 0.82 | CARM1 (0.45) | MCHR1CARM1PRMT6CCNT1ALDH1A1 | |
| SCHEMBL4260562 | 0.82 | CARM1 (0.45) | MCHR1CARM1PRMT6CCNT1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4262316 | 0.80 | MCHR1 (0.40) | MCHR1CARM1PRMT6ADRA2A | |
| SCHEMBL4260890 | 0.80 | ALDH1A1 (0.52) | MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | MCHR1 3/4885CARM1 1492/4885PRMT6 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.