Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878892 | 1.00 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4076080 | 1.00 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4072166 | 0.92 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13878888 | 0.92 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4072165 | 0.92 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13479086 | 0.88 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31179023 | 0.88 | MAPT (0.43) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14602205 | 0.85 | MAPT (0.62) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13878881 | 0.85 | MAPT (0.62) | MAPTNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL496007 | 0.83 | NFE2L2 (0.35) | MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PC, GOT2, PDK1 | MAPT 3617/4885NPSR1 3018/4885SMN1; SMN2 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.