Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.62 |
| ▸ | CA12 | O43570 | 7/20 | 0.62 |
| ▸ | CA9 | Q16790 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322731 | 0.85 | MEN1 (0.71) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL6677569 | 0.85 | POLB (0.60) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL6810312 | 0.85 | MEN1 (0.52) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL4436535 | 0.85 | MEN1 (0.52) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL9788043 | 0.84 | POLB (0.58) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL14467528 | 0.83 | MEN1 (0.76) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL29747008 | 0.80 | MAPK1 (0.53) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL28584350 | 0.80 | CA2 (0.54) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL8619132 | 0.80 | MEN1 (0.46) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL187588 | 0.78 | TDP1 (0.55) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831587-A1 | SIGNALING CONJUGATES AND METHODS OF USE | Ventana Medical Systems, Inc. (US) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013148498-A1 | SIGNALING CONJUGATES AND METHODS OF USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2013-10-03 | — | — | WO | disclosed |
| EP-2588443-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | Ventana Medical Systems, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003476-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |