Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677569 | 0.98 | POLB (0.60) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL4436535 | 0.84 | MEN1 (0.52) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL6810312 | 0.84 | MEN1 (0.52) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL16322731 | 0.84 | MEN1 (0.71) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL42642 | 0.84 | CA2 (0.62) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL16566766 | 0.83 | POLB (0.55) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL16566903 | 0.81 | POLB (0.53) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL5485815 | 0.80 | HTR6 (0.47) | POLBCYP2D6MEN1KMT2AMAPT | |
| SCHEMBL5485813 | 0.80 | HTR6 (0.44) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29747008 | 0.79 | MAPK1 (0.53) | POLBCYP2D6MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073171-A | Solid polymeric body incorporating an albumin-binding dye to form a protective coating; anticoagulants; antiinflammatory agents | EATON JOHN W (US) | 1991-12-17 | — | — | US | disclosed |