Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 1.00 |
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA9 | Q16790 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | F2 | P00734 | 3/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42659 | 1.00 | CA2 (1.00) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL330045 | 0.88 | CA2 (0.78) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL15631068 | 0.85 | NPC1 (0.73) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL9019288 | 0.83 | NPC1 (0.71) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL13602555 | 0.83 | NPC1 (0.71) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL14419936 | 0.83 | NPC1 (0.71) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL13384871 | 0.83 | NPC1 (0.71) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL8492321 | 0.82 | CA2 (0.70) | CA2CA12CA9MEN1NPC1 | |
| SCHEMBL42344 | 0.81 | NPC1 (0.69) | CA2CA12CA9MEN1NPC1 | |
| Methyl Orange SCHEMBL296471 | 0.81 | NPC1 (0.69) | CA2CA12CA9MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240123045-A1 | NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS | BRENUS PHARMA (FR) | 2024-04-18 | — | — | US | claimed |
| EP-4297874-A1 | NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS | BRENUS PHARMA (FR) | 2024-01-03 | — | — | EP | claimed |
| US-11780863-B2 | Quinone methide analog signal amplification | VENTANA MEDICAL SYSTEMS, INC. (US) | 2023-10-10 | — | — | US | claimed |
| EP-3377530-B1 | METHODS OF IDENTIFYING IMMUNE CELLS IN PD-L1 POSITIVE TUMOR TISSUE | VENTANA MED SYST INC (US) | 2021-06-30 | — | — | EP | claimed |
| US-20200271662-A1 | PROXIMITY ASSAYS USING CHEMICAL LIGATION AND HAPTEN TRANSFER | VENTANA MED SYST INC (US) | 2020-08-27 | — | — | US | claimed |
| EP-2686438-B1 | A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFOR | VENTANA MED SYST INC (US) | 2018-04-18 | — | — | EP | claimed |
| EP-2686438-A1 | A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE | Ventana Medical Systems, Inc. (US) | 2014-01-22 | — | — | EP | claimed |
| EP-2539355-A1 | POLYTAG PROBES | Ventana Medical Systems, Inc. (US) | 2013-01-02 | — | — | EP | claimed |
| EP-2539466-A1 | CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES | Ventana Medical Systems, Inc. (US) | 2013-01-02 | — | — | EP | claimed |
| US-20120301886-A1 | POLYTAG PROBES | VENTANA MEDICAL SYSTEMS, INC. | 2012-11-29 | — | — | US | claimed |
| US-20120301885-A1 | CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES | TANG LEI (US) | 2012-11-29 | — | — | US | claimed |
| US-20120237930-A1 | METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE | VENTANA MEDICAL SYSTEMS, INC. | 2012-09-20 | — | — | US | claimed |
| WO-2012123387-A1 | A METHOD OF ANALYZING CHROMOSOMAL TRANSLOCATIONS AND A SYSTEM THEREFORE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | claimed |
| WO-2011106495-A1 | CYTOGENIC ANALYSIS OF METAPHASE CHROMOSOMES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| WO-2011106583-A1 | POLYTAG PROBES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2011-09-01 | — | — | WO | claimed |
| US-20240123045-A1 | NONAUTOLOGOUS MULTI-STRESSED CANCER CELLS AND USES THEREOF FOR VACCINATING AND TREATING CANCERS | BRENUS PHARMA (FR) | 2024-04-18 | — | — | US | disclosed |
| US-20240069034-A1 | PROXIMITY ASSAYS USING CHEMICAL LIGATION AND HAPTEN TRANSFER | VENTANA MED SYST INC (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2008063378-A2 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| EP-0877616-A1 | MEDICAMENTS CONTAINING AROMATIC AZO COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026890-A1 | MEDICAMENTS CONTAINING AROMATIC AZO COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780863-B2 | Quinone methide analog signal amplification | NQO2, SQOR, MRM1 | CA2 2563/4885CA12 1792/4885CA9 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.