Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | CA12 | O43570 | 4/20 | 0.71 |
| ▸ | CA2 | P00918 | 4/20 | 0.71 |
| ▸ | CA9 | Q16790 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | F2 | P00734 | 3/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893140 | 0.88 | ALDH1A1 (0.57) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL15631068 | 0.86 | NPC1 (0.73) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL14419936 | 0.85 | NPC1 (0.71) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL13602555 | 0.85 | NPC1 (0.71) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL13384871 | 0.85 | NPC1 (0.71) | NPC1RAB9AKMT2ACA12CA2 | |
| Methyl Orange SCHEMBL18892 | 0.83 | KMT2A (0.69) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL7764334 | 0.83 | NPC1 (0.69) | NPC1RAB9AKMT2ACA12CA2 | |
| Methyl Orange SCHEMBL296471 | 0.83 | NPC1 (0.69) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL42344 | 0.83 | NPC1 (0.69) | NPC1RAB9AKMT2ACA12CA2 | |
| SCHEMBL42343 | 0.83 | NPC1 (0.69) | NPC1RAB9AKMT2ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650595-A4 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF. | PATCHORNIK ZIPORA (IL) | 1996-08-21 | — | — | EP | claimed |
| EP-0650595-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, Zipora (IL) | 1995-05-03 | — | — | EP | claimed |
| WO-1994001771-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, ZIPORA (IL) | 1994-01-20 | — | — | WO | claimed |