Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976198 | 0.89 | MAPT (0.53) | MAPTALDH1A1L3MBTL1TSHRCYP1A2 | |
| SCHEMBL974894 | 0.89 | MAPT (0.53) | MAPTALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL25624811 | 0.84 | MAPT (0.45) | MAPTALDH1A1L3MBTL1GAANPSR1 | |
| SCHEMBL978044 | 0.81 | SIGMAR1 (0.41) | MAPTALDH1A1L3MBTL1TSHRNPSR1 | |
| SCHEMBL4762870 | 0.78 | MAPT (0.56) | MAPTALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL9572889 | 0.75 | MAPT (0.52) | MAPTALDH1A1L3MBTL1TSHRCYP1A2 | |
| SCHEMBL20626603 | 0.73 | MAPT (0.50) | MAPTALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL15736855 | 0.72 | TSHR (0.35) | MAPTTSHRHTTMEN1KMT2A | |
| SCHEMBL18922359 | 0.72 | MAPT (0.48) | MAPTALDH1A1L3MBTL1GAANPSR1 | |
| SCHEMBL5328752 | 0.72 | TGM2 (0.39) | MAPTALDH1A1L3MBTL1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197591-B2 | Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof | ECKART GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20090249979-A1 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |