Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976198 | 0.97 | MAPT (0.53) | MAPTALDH1A1L3MBTL1KCNH3TSHR | |
| SCHEMBL4264763 | 0.89 | MAPT (0.47) | MAPTALDH1A1L3MBTL1KCNH3TSHR | |
| SCHEMBL978044 | 0.78 | SIGMAR1 (0.41) | MAPTALDH1A1L3MBTL1TSHRCYP1A2 | |
| SCHEMBL16714737 | 0.78 | MAOA (0.56) | MAPTDRD4KDM4EHDAC3HDAC1 | |
| SCHEMBL28350472 | 0.76 | MAPT (0.46) | MAPTALDH1A1L3MBTL1KCNH3PPARG | |
| SCHEMBL2157273 | 0.76 | MAPT (0.53) | MAPTALDH1A1L3MBTL1KCNH3TSHR | |
| SCHEMBL16714770 | 0.75 | MAOA (0.61) | MAPTDRD4KDM4EHDAC3HDAC1 | |
| SCHEMBL3788882 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1L3MBTL1KCNH3CYP1A2 | |
| SCHEMBL15735832 | 0.74 | MEN1 (0.37) | MAPTTSHRHTT | |
| SCHEMBL25624811 | 0.74 | MAPT (0.45) | MAPTALDH1A1L3MBTL1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289898-B1 | Melamine-functional organosilicon compound and making method | SHINETSU CHEMICAL CO (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-8263766-B2 | Melamine-functional organosilicon compound and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| EP-2289898-A1 | Melamine-Functional organosilicon compound and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-20110003989-A1 | MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003989-A1 | MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD | MEN1, MSH6, PRMT6 | MAPT 1317/4885ALDH1A1 3030/4885L3MBTL1 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.