SCHEMBL978044

SCHEMBL978044

CC(C)(CNc1ccccc1)O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.41
MAPT P10636 4/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
HTT P42858 2/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CTSD P07339 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17700506 0.82 MAPT (0.42) SIGMAR1MAPTALDH1A1TSHRL3MBTL1
SCHEMBL4264763 0.81 MAPT (0.47) SIGMAR1MAPTALDH1A1TSHRL3MBTL1
SCHEMBL975249 0.79 SIGMAR1 (0.41) SIGMAR1MAPTALDH1A1TSHRL3MBTL1
SCHEMBL974894 0.78 MAPT (0.53) MAPTALDH1A1TSHRL3MBTL1CYP1A2
SCHEMBL976198 0.78 MAPT (0.53) MAPTALDH1A1TSHRL3MBTL1CYP1A2
SCHEMBL3732806 0.76 MAPT (0.48) SIGMAR1MAPTALDH1A1TSHRL3MBTL1
SCHEMBL28050815 0.76 CA12 (0.38) SIGMAR1MAPTALDH1A1L3MBTL1MEN1
Hydrochloric Acid SCHEMBL17710416 0.74 MAPT (0.46) SIGMAR1MAPTALDH1A1TSHRL3MBTL1
SCHEMBL5401394 0.73 PRSS1 (0.46) MAPTALDH1A1MEN1KMT2ACA2
SCHEMBL15114128 0.72 MAPT (0.50) SIGMAR1MAPTALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240868-B2 Organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-04 US disclosed
EP-3783037-B1 POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR SHINETSU CHEMICAL CO (JP) 2024-01-10 EP disclosed
CN-111989348-B Polymer having reactive silicon-containing group and method for producing same 信越化学工业株式会社 2023-10-20 CN disclosed
CN-111989333-B Organosilicon compound and method for producing same 信越化学工业株式会社 2023-09-15 CN disclosed
US-11667790-B2 Polymer having reactive silicon-containing group and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-06 US disclosed
US-20210163512-A1 ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-03 US disclosed
US-20210155800-A1 POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-27 US disclosed
EP-3783037-A1 POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2021-02-24 EP disclosed
EP-3783003-A1 ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR Shin-Etsu Chemical Co., Ltd. (JP) 2021-02-24 EP disclosed
CN-111989348-A Polymer having reactive silicon-containing group and method for producing same 信越化学工业株式会社 2020-11-24 CN disclosed
US-20110003989-A1 MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-01-06 US disclosed
EP-1904587-B1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2010-11-03 EP disclosed
US-20090249979-A1 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2009-10-08 US disclosed
EP-1904587-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCITON THEREOF Eckart GmbH (DE) 2008-04-02 EP disclosed
WO-2008015123-A1 PREPARATION OF ACID DERIVATIVE-FUNCTIONAL ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
WO-2007098887-A2 PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING α-SILANES AND METHOD FOR THE PRODUCITON THEREOF ECKART GMBH (DE) 2007-09-07 WO disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003989-A1 MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD MEN1, MSH6, PRMT6 SIGMAR1 2547/4885MAPT 1317/4885ALDH1A1 3030/4885
US-20210163512-A1 ORGANIC SILICON COMPOUND AND PRODUCTION METHOD THEREFOR OR51E2, MSL1, SOS1 SIGMAR1 537/4885MAPT 3942/4885ALDH1A1 2353/4885
US-12240868-B2 Organic silicon compound and production method therefor OR51E2, MSL1, SOS1 SIGMAR1 537/4885MAPT 3942/4885ALDH1A1 2353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.