Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898123 | 0.82 | TTR (0.48) | TPMT | |
| SCHEMBL11878620 | 0.80 | CA1 (0.41) | TPMTALDH1A1TSHR | |
| SCHEMBL8724553 | 0.80 | TPMT (0.41) | TPMT | |
| SCHEMBL38576 | 0.76 | ALDH1A1 (0.40) | TPMTALDH1A1TSHR | |
| SCHEMBL28699581 | 0.76 | TPMT (0.35) | TPMTALDH1A1TSHR | |
| SCHEMBL122324 | 0.76 | TPMT (1.00) | TPMTALDH1A1TSHR | |
| SCHEMBL913884 | 0.76 | TPMT (0.35) | TPMTALDH1A1TSHR | |
| SCHEMBL25779809 | 0.75 | TPMT (0.39) | TPMTALDH1A1TSHR | |
| SCHEMBL16384672 | 0.75 | TPMT (0.34) | TPMTALDH1A1TSHR | |
| SCHEMBL22991650 | 0.74 | TPMT (0.48) | TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142853-A | BENZOYLATION | SHIKIBO LIMITED (JP) | 1979-03-06 | — | — | US | claimed |
| CN-107915832-B | X-ray developed iodine-containing polycarbonate/polyester material and preparation method and application thereof | 复旦大学 | 2020-07-28 | — | — | CN | disclosed |
| US-9259515-B2 | Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-02-16 | — | — | US | disclosed |
| US-8507639-B2 | Polyamide block polymers containing iodoarylcarboxyl pendant groups and modified poly(meth)acrylamide; coupling; for tracking movement of a catheter through the body or inflation of balloon at site | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20090326642-A1 | Implantable Medical Devices Fabricated From Radiopaque Polymers With High Fracture Toughness | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2009-12-31 | — | — | US | disclosed |
| US-20090259297-A1 | Implantable Medical Devices Fabricated From Polyurethanes With Grafted Radiopaque Groups | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2009-10-15 | — | — | US | disclosed |
| EP-2066362-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | Boston Scientific Limited (BB) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008033198-A1 | RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF | BOSTON SCIENTIFIC LIMITED (BB) | 2008-03-20 | — | — | WO | disclosed |
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1997026300-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |
| US-5605896-A | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-02-25 | — | — | US | disclosed |
| EP-0423251-A4 | ASSAY FOR QUALITATIVE AND QUANTITATIVE DETECTION OF ORGANIC AND INORGANIC ANALYTES OF DIVERSE CHEMICAL CLASSES VIA THE SELECTIVE FORMATION AND GROWTH OF LIGHT SCATTERING CRYSTALS | — | 1993-06-09 | — | — | EP | disclosed |
| US-4142853-A | BENZOYLATION | SHIKIBO LIMITED (JP) | 1979-03-06 | — | — | US | disclosed |