Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 2/20 | 0.45 |
| ▸ | JUN | P05412 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217525 | 0.90 | HSD17B10 (0.49) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL13952660 | 0.86 | NPC1 (0.40) | L3MBTL1LTB4RHSD17B10ALDH1A1FOS | |
| SCHEMBL4264820 | 0.84 | TSHR (0.58) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL8214127 | 0.81 | TAS1R3 (0.55) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL4260941 | 0.80 | MAPT (0.55) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL4257689 | 0.80 | KMT2A (0.55) | HSD17B10ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL10955996 | 0.80 | PDE4B (0.55) | L3MBTL1LTB4RHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL10919270 | 0.78 | CYSLTR2 (0.69) | CYP1A2CYSLTR2CYSLTR1 | |
| SCHEMBL4272863 | 0.77 | ALDH1A1 (0.57) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL9120028 | 0.76 | CTNNB1 (0.49) | L3MBTL1HSD17B10ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | L3MBTL1 2152/4885LTB4R 3889/4885HSD17B10 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.