Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2975839 | 0.99 | HPGDS (0.52) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| SCHEMBL2978210 | 0.81 | MAOA (0.42) | SMN1; SMN2RAB9AMAOAARTP53 | |
| SCHEMBL3772350 | 0.80 | HPGDS (0.59) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| SCHEMBL4262100 | 0.80 | HPGDS (0.59) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| SCHEMBL4259512 | 0.80 | HPGDS (0.59) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| SCHEMBL2297392 | 0.79 | HPGDS (0.78) | HPGDSSMN1; SMN2RAB9AARTP53 | |
| SCHEMBL4265265 | 0.79 | HPGDS (0.61) | HPGDSSMN1; SMN2RAB9AARBAZ2A | |
| Bromide SCHEMBL2983628 | 0.79 | HPGDS (0.57) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL1653293 | 0.79 | ALDH1A1 (0.58) | HPGDSSMN1; SMN2RAB9AMAOAMAOB | |
| Bromide SCHEMBL2979882 | 0.79 | HPGDS (0.57) | HPGDSSMN1; SMN2RAB9AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945635-B1 | THIAZOLYL PIPERIDINE DERIVATIVES USEFUL AS H3 RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2009-05-06 | — | — | EP | disclosed |