SCHEMBL4266012

SCHEMBL4266012

CCC[SiH2]OC(CC)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
KCNN4 O15554 1/20 0.35
MAPK1 P28482 1/20 0.34
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
KDM4E B2RXH2 2/20 0.32
NR1I2 O75469 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2E1 P05181 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C8 P10632 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP4B1 P13584 1/20 0.31
CYP2B6 P20813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704048 0.92 KCNN4 (0.38) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL707299 0.89 KCNN4 (0.35) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL704100 0.89 KCNN4 (0.35) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL706839 0.88 KCNN4 (0.38) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL4265415 0.87 LMNA (0.36) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL4281342 0.86 KCNN4 (0.36) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL704018 0.81 KCNN4 (0.35) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL4281338 0.80 KCNN4 (0.38) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL5024578 0.78 TAAR1 (0.38) LMNAKCNN4MAPK1TAAR1ALDH1A1
SCHEMBL706316 0.78 LMNA (0.33) LMNAKCNN4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7604866-B2 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2009-10-20 US disclosed
US-20060269724-A1 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-11-30 US disclosed