Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3593426 | 0.99 | ALOX5 (0.48) | ALOX5ATMSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4264273 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL30557800 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL3607612 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL3603512 | 0.84 | ALOX5 (0.43) | ALOX5LMNAALDH1A1HTR2AHTR2C | |
| SCHEMBL17062844 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HTR2CF10F2 | |
| SCHEMBL3601344 | 0.82 | HTR2A (0.49) | ALOX5HTR2AHTR2CHTR2BF10 | |
| Hydrochloric Acid SCHEMBL3602862 | 0.81 | HTR2A (0.48) | ALOX5HTR2AHTR2CHTR2BF10 | |
| SCHEMBL3597573 | 0.80 | ADRB1 (0.48) | ALOX5HTR2AHTR2CHTR2BKHK | |
| Hydrochloric Acid SCHEMBL3603535 | 0.79 | ADRB1 (0.47) | ALOX5HTR2AHTR2CHTR2BKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039695-A1 | BICYCLIC HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-03-25 | — | — | EP | disclosed |