SCHEMBL4267157

SCHEMBL4267157

COC(=O)CCCCCOc1c2ccoc2cc2oc(=O)ccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNA3 P22001 19/20 0.69
▸ KCNA5 P22460 12/20 0.67
▸ KCNN4 O15554 1/20 0.64
▸ THRB P10828 1/20 0.64
▸ KCNA2 P16389 1/20 0.64
▸ KCNA6 P17658 1/20 0.64
▸ KCNA4 P22459 1/20 0.64
▸ KCNA1 Q09470 1/20 0.64
▸ KCNMA1 Q12791 1/20 0.64
▸ KCNH2 Q12809 1/20 0.64
▸ KCNN1 Q92952 1/20 0.64
▸ KCNA7 Q96RP8 1/20 0.64
▸ KCNN2 Q9H2S1 1/20 0.64
▸ CYP2D6 P10635 2/20 0.62
▸ CYP2C19 P33261 2/20 0.62
▸ CYP1A1 P04798 1/20 0.62
▸ CYP2B6 P20813 1/20 0.62
▸ CYP3A43 Q9HB55 1/20 0.62
▸ KDM4E B2RXH2 1/20 0.61
▸ ALDH1A1 P00352 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27293969 0.92 KCNA3 (0.65) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL4269808 0.85 ALDH1A1 (0.65) KCNA3KCNA5THRBKCNA2CYP2D6
SCHEMBL4268685 0.83 KCNA2 (0.60) KCNA3KCNA5KCNA2CYP1A1KDM4E
SCHEMBL2586620 0.82 KCNA3 (0.98) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL2583842 0.82 KCNA3 (1.00) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL7754086 0.81 KCNA3 (0.71) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL2586445 0.81 KCNA3 (0.76) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL29503682 0.81 KCNA3 (0.71) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL2585968 0.81 KCNA3 (1.00) KCNA3KCNA5KCNN4THRBKCNA2
SCHEMBL2586243 0.81 KCNA3 (1.00) KCNA3KCNA5KCNN4THRBKCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 — — US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 — — US disclosed
US-8802892-B2 Functionalized phenolic compounds and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-08-12 — — US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 — — US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 — — US disclosed
US-20130281652-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC 2013-10-24 — — US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 — — US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 — — US disclosed
US-8318973-B2 Functionalized sinapic acid and methyl sinapate BEZWADA BIOMEDICAL, LLC (US) 2012-11-27 — — US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 — — US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 — — US disclosed
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-07-02 — — US disclosed
EP-1951260-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM Bezwada Biomedical LLC (US) 2008-08-06 — — EP disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 — — WO disclosed
WO-2007053794-A2 FUNCTIONALIZED PHENOLIC COMPOUNDS AND ABSORBABLE THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-05-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170927-A1 FUNCTIONALIZED PHENOLIC COMPOUNDS AND POLYMERS THEREFROM COMT, AOX1, UGT1A6 KCNA3 2918/4885KCNA5 2106/4885KCNN4 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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