Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30871932 | 0.87 | KMO (0.48) | KMOUSP2HTTALOX15POLB | |
| SCHEMBL13780087 | 0.80 | KMO (0.58) | KMOUSP2HTTALOX15POLB | |
| SCHEMBL14615631 | 0.80 | KMO (0.55) | KMOUSP2HTTALOX15POLB | |
| 6-F-D-Diboa SCHEMBL4261735 | 0.80 | ALDH1A1 (0.41) | KMOHTTPOLBKDM4EMAPT | |
| SCHEMBL4258598 | 0.80 | TSHR (0.51) | KMOUSP2HTTPOLBMEN1 | |
| SCHEMBL14016381 | 0.78 | KMO (0.56) | KMOUSP2HTTALOX15POLB | |
| SCHEMBL5342839 | 0.78 | CYP1A2 (0.43) | KMOUSP2HTTPOLBMEN1 | |
| SCHEMBL12203796 | 0.76 | USP2 (0.67) | KMOUSP2HTTALOX15POLB | |
| SCHEMBL13140225 | 0.76 | KMO (0.51) | KMOUSP2HTTALOX15POLB | |
| 6-Cf3-D-Diboa SCHEMBL4260480 | 0.76 | TERT (0.47) | KMOHTTPOLBMAPTSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059850-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | UNIVERSIDAD DE CÁDIZ (ES) | 2011-03-10 | — | — | US | claimed |
| EP-2048136-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | Universidad de Cadiz (ES) | 2009-04-15 | — | — | EP | disclosed |