Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPR1 | P16066 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-F-D-Diboa SCHEMBL4261735 | 0.80 | ALDH1A1 (0.41) | TSHRCYP1A2CYP3A4TP53HTT | |
| SCHEMBL30336556 | 0.80 | PDE3B (0.54) | TSHRCYP1A2CYP3A4TP53PKM | |
| 6-Cl-D-Diboa SCHEMBL4267274 | 0.80 | KMO (0.58) | TSHRHTTKMOSLC5A1SLC5A2 | |
| SCHEMBL265087 | 0.80 | PDE3B (0.54) | TSHRCYP1A2CYP3A4TP53PKM | |
| SCHEMBL16184461 | 0.78 | HTT (0.51) | TSHRCYP1A2CYP3A4TP53PKM | |
| SCHEMBL5342839 | 0.78 | CYP1A2 (0.43) | TSHRCYP1A2CYP3A4TP53HTT | |
| SCHEMBL28636025 | 0.76 | TSHR (0.48) | TSHRCYP1A2CYP3A4TP53PKM | |
| 6-Cf3-D-Diboa SCHEMBL4260480 | 0.76 | TERT (0.47) | TSHRTP53HTTKMOALDH1A1 | |
| SCHEMBL3660420 | 0.76 | BRD4 (0.58) | TSHRHTTKMOALDH1A1SLC5A1 | |
| SCHEMBL2748218 | 0.75 | TSHR (0.53) | TSHRTP53HTTALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059850-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | UNIVERSIDAD DE CÁDIZ (ES) | 2011-03-10 | — | — | US | claimed |
| EP-2048136-A1 | PHYTOTOXIC HALOGENATED DERIVATIVES OF BENZOXAZINONES | Universidad de Cadiz (ES) | 2009-04-15 | — | — | EP | disclosed |
| US-7205295-B2 | Benzoxazin-3-ones and derivatives thereof as therapeutic agents | WARNER-LAMBERT COMPANY LLC (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1569653-A1 | BENZOXAZIN-3-ONES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3K | Warner-Lambert Company LLC (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052373-A1 | BENZOXAZIN-3-ONES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3K | WARNER-LAMBERT COMPANY LLC (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040121996-A1 | Benzoxazin-3-ones and derivatives thereof as therapeutic agents | BARVIAN NICOLE (US) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121996-A1 | Benzoxazin-3-ones and derivatives thereof as therapeutic agents | XDH, HAX1, CYP4X1 | TSHR 2417/4885CYP1A2 269/4885CYP3A4 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.