Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582208 | 0.84 | HSP90AA1 (0.56) | HSP90AA1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL3099503 | 0.82 | LMNA (0.53) | HSP90AA1KMT2ANPC1RAB9A | |
| SCHEMBL15300346 | 0.77 | HSP90AA1 (0.42) | HSP90AA1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL4270537 | 0.76 | HSP90AA1 (0.46) | HSP90AA1MAPTPTGDR2NPC1RAB9A | |
| SCHEMBL4263747 | 0.74 | HSP90AA1 (0.52) | HSP90AA1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL3078123 | 0.72 | MEN1 (0.50) | HSP90AA1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL4267221 | 0.72 | HPGD (0.55) | HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL4261422 | 0.71 | HSD11B1 (0.46) | HSP90AA1NPC1RAB9A | |
| SCHEMBL4267349 | 0.71 | HSP90AA1 (0.47) | HSP90AA1MAPTNPC1RAB9ATP53 | |
| SCHEMBL4993433 | 0.71 | P2RX7 (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076001-A1 | Substituted 4,5,6,7 -Tetrahydro-Isoxazolo[4,5-C]Pyridine Compounds and Use Thereof for Producing Medicaments | GRUENENTHAL GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076001-A1 | Substituted 4,5,6,7 -Tetrahydro-Isoxazolo[4,5-C]Pyridine Compounds and Use Thereof for Producing Medicaments | P2RX5, P2RX4, P2RX7 | HSP90AA1 3575/4885MAPT 3693/4885THRB 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.